Tiré du Pharmacist's Letter de mai
Routine monitoring is NOT helpful.
Statins can increase liver enzymes but it's usually transient.
Any serious liver injury due to statins is idiosyncratic and therefore isn't prevented with routine monitoring.
Liver failure itself is very rare if it happens at all.
There's only about one case of liver failure for every million patients per year on a statin... the same as for people not on a statin.
Tell patients the new recommendation is to check liver enzymes BEFORE starting a statin and then only if they have symptoms, such as unexplained nausea, abdominal pain or jaundice.
15 mai 2012
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